SURGICAL TREATMENT OF CHRONIC HEMORRHOIDS IN PATIENTS WITH DRUG HYPOCOAGULATION

Authors

  • Rashid Ruzibayev Md, Phd, Professor, Director Of The Urgench Branch Of Tashkent Medical Academy, Urgench, Uzbekistan
  • Doniyor Umarov Md, Assistant Of The Department Of Surgery, Urgench Branch Of Tashkent Medical Academy, Urgench, Uzbekistan

Keywords:

Experimental study, morphology,, model of anus wound, drug hypocoagulation, hemostasis, “Heprocel”

Abstract

Today, hemorrhoids are characterized by their relevance among coloproctological diseases. There is a lot of data on the pathogenesis and course of hemorrhoidal disease, the clinical picture of hemorrhoids, which is diverse in a wide range and requires careful differential diagnosis. Thus, we set a goal to study the results of surgical treatment of chronic stage III-IV hemorrhoids in patients with drug-induced hypocoagulation.

Material and methods. We studied 230 patients with chronic combined stage III-IV hemorrhoids, concomitant cardiovascular pathology. The groups were matched by sex, age, type and severity of pathology, as well as the type of surgical intervention. In the main group - 112 patients with chronic combined hemorrhoids and drug hypocoagulation for concomitant cardiovascular pathology, Milligan-Morgan hemorrhoidectomy was combined with the proposed method of enhancing the local hemostatic effect by using the domestic hemostatic agent "Heprocel" in the form of a gel.

The results showed that the application of a hemostatic agent in the area of tissues dissected in the anal sphincter region, due to its high adhesiveness and barrier function, made it possible to reduce the intensity of the pain syndrome.

Downloads

References

Aigner F, Gruber H, Conrad F, Eder J, Wedel T, Zelger B, Engelhardt V, Lametschwandtner A, Wienert V, Böhler U, Margreiter R, Fritsch H. Revised morphology and hemodynamics of the anorectal vascular plexus: impact on the course of hemorrhoidal disease. Int J Colorectal Dis. 2009 Jan;24(1):105-13. doi: 10.1007/s00384-008-0572-3.

Lin HC, He QL, Shao WJ, Chen XL, Peng H, Xie SK, Wang XX, Ren DL. Partial Stapled Hemorrhoidopexy Versus Circumferential Stapled Hemorrhoidopexy for Grade III to IV Prolapsing Hemorrhoids: A Randomized, Noninferiority Trial. Dis Colon Rectum. 2019 Feb;62(2):223-233. doi: 10.1097/DCR.0000000000001261.

Margetis N. Pathophysiology of internal hemorrhoids. Ann Gastroenterol. 2019 May-Jun;32(3):264-272. doi: 10.20524/aog.2019.0355. Epub 2019 Jan 23. PMID: 31040623; PMCID: PMC6479658.

Pata F, Sgró A, Ferrara F, Vigorita V, Gallo G, Pellino G. Anatomy, Physiology and Pathophysiology of Haemorrhoids. Rev Recent Clin Trials. 2021;16(1):75-80. doi: 10.2174/1574887115666200406115150.

Zagriadskiǐ E.A, Bogomazov A.M, Golovko EB. Conservative Treatment of Hemorrhoids: Results of an Observational Multicenter Study. Adv Ther. 2018;35(11):1979-92.

Downloads

Published

2021-11-09

How to Cite

Rashid Ruzibayev, & Doniyor Umarov. (2021). SURGICAL TREATMENT OF CHRONIC HEMORRHOIDS IN PATIENTS WITH DRUG HYPOCOAGULATION. International Scientific and Current Research Conferences, 1(01), 45–48. Retrieved from https://www.orientalpublication.com/index.php/iscrc/article/view/110