EFFECT OF VITAMIN D ON INFLAMMATORY CYTOKINES IN CHRONIC HEART FAILURE

Authors

  • Abdigaffar G. Gadaev Researcher Tashkent Medical Academy, Uzbekistan
  • Shovkat Sh. Quchkorov esearcher Fergana Public Health Medical Institute, Uzbekistan
  • Nilufar A. Gadaeva Researcher Tashkent Medical Academy, Uzbekistan

Keywords:

Chronic heart failure (CHF), ischemic heart disease (IHD), endocrine

Abstract

In patients with chronic heart failure, serum vitamin D levels fluctuate in association with inflammatory cytokine markers. Also, on the basis of standard treatment, the combined use of sodium glucose type 2 inhibitor empagliflozin and vitamin D has been found to have a positive effect on inflammatory cytokines and vitamin D indicators.

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References

Altay H, Colkesen Y. Parathyroid hormone and heart failure: novel biomarker strategy. Endocr Metab Immune Disord Drug Targets. 2013;13:100–104.

Altay H, Zorlu A, Binici S, et al. Relation of serum parathyroid hormone level to severity of heart failure. Am J Cardiol. 2012;109:252–256.

Briasoulis A., Androulakis, E., Christophides, T. et al. The role of inflammation and cell death in the pathogenesis, progression and treatment of heart failure // Heart failure reviews. - 2016. - T. 21. - №. 2. - C. 169-176.

Chronic heart failure: epidemiology, investigation and management Simon A.S. Beggs Theresa A. McDonagh Roy S. Gardner Heart Muscle Disease| Volume 50, ISSUE 8, P479-486, AUGUST 2022 DOI:https://doi.org/10.1016/j.mpmed.2022.05.002.

Courbebaisse, M., and Lanske, B. (2018). Biology of fibroblast growth factor 23: from physiology to pathology. Cold Spring Harb. Perspect. Med. 8:a031260. doi: 10.1101/cshperspect.a031260.

Evenepoel P, Meijers B, Viaene L, Bammens B, Claes K, Kuypers D et al. Fibroblast growth factor-23 in early chronic kidney disease: additional support in favor of a phosphate-centric paradigm for the pathogenesis of secondary hyperparathyroidism. Clin J Am Soc Nephrol. 2010;5(7):1268–76.

Fontes J. A., Rose N. R., Cihakova D. The varying faces of IL-6: From cardiac protection to cardiac failure // Cytokine. - 2015. - T. 74. - №. 1. - C.62-68.

Global burden of heart failure: a comprehensive and updated review of epidemiology. Cardiovasc Res. 2023 Jun 13;119(6):1453. doi: 10.1093/cvr/cvad026. Erratum for: Cardiovasc Res. 2023 Jan 18;118(17):3272-3287. PMID: 36754553; PMCID: PMC10262176.

Gullestad L, Ueland T, Vinge LE, et al. Inflammatory cytokines in heart failure: mediators and markers. Cardiology. 2012;122:23–35.

Hartupee J, Mann DL. Positioning of inflammatory biomarkers in the heart failure landscape. J Cardiovasc Transl Res. 2013;6:485–492.

Jiang WL, Gu HB, Zhang YF, Xia QQ, Qi J, Chen JC. Vitamin D Supplementation in the Treatment of Chronic Heart Failure: A Meta-analysis of Randomized Controlled Trials. Clin Cardiol. 2016 Jan;39(1):56-61. doi: 10.1002/clc.22473.

Kristal-Boneh E, Froom P, Harari G, Ribak J. Association of calcitriol and blood pressure in normotensive men. Hypertension. 1997;30 (5):1289–94.

Liu LCY, Voors AA, van Veldhuisen DJ, van der Veer E, Belonje AM, Szymanski MK et al. Vitamin D status and outcomes in heart failure patients. Eur J Heart Fail. 2011;13 (6):619–25.

Ponikowski P. et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart fai lure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur. J. Heart Fail.2016; 18(8): 891-975.

Shedeed SA. Vitamin D supplementation in infants with chronic congestive heart failure. Pediatr Cardiol. 2012;33:713–719.

Vitamin D deficiency and insufficiency among US adults: prevalence, predictors and clinical implications. Liu X, Baylin A, Levy PD. Br J Nutr. 2018;119:928–936.

von Haehling S, Lainscak M, Springer J, Anker SD. Cardiac cachexia: a systematic overview. Pharmacol Ther 2009;121:227–52.

Weeda E.R., Nguyen E., White C.M. The Role of Ivabradine in the Treatment of Patients with Cardiovascular Disease // Ann Pharmacother. - 2016. - Vol. 50. - P. 475 - 485.

Witham MD, Crighton LJ, Gillespie ND, et al. The effects of vitamin D supplementation on physical function and quality of life in older patients with heart failure: a randomized controlled trial. Circ Heart Fail. 2010;3:195–201.

Zipes DP. Warning: the short days of winter may be hazardous to your health. Circulation. 1999;100:1590-1592.

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Published

2024-04-30

How to Cite

Abdigaffar G. Gadaev, Shovkat Sh. Quchkorov, & Nilufar A. Gadaeva. (2024). EFFECT OF VITAMIN D ON INFLAMMATORY CYTOKINES IN CHRONIC HEART FAILURE. International Scientific and Current Research Conferences, 1(01), 107–114. Retrieved from https://www.orientalpublication.com/index.php/iscrc/article/view/1525

Issue

2024: MIND, MATTER, AND MEANING: UNITING NEUROSCIENCE, PHILOSOPHY, AND COGNITIVE SCIENCE

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Articles

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Copyright (c) 2024 Abdigaffar G. Gadaev, Shovkat Sh. Quchkorov, Nilufar A. Gadaeva

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