CHANGE IN THE HEMOSTASIS SYSTEM UNDER THE INFLUENCE OF AN HSS-23

Authors

  • Khoshimov N.N. Institute Of Biophysics And Biochemistry At The National University Of Uzbekistan Named After Mirzo Ulugbek, Tashkent, Uzbekistan
  • Ortikov M.M Institute Of Biophysics And Biochemistry At The National University Of Uzbekistan Named After Mirzo Ulugbek, Tashkent, Uzbekistan
  • Dedaboev J.I. Institute Of Biophysics And Biochemistry At The National University Of Uzbekistan Named After Mirzo Ulugbek, Tashkent, Uzbekistan
  • Nasirov K.E. Institute Of Biophysics And Biochemistry At The National University Of Uzbekistan Named After Mirzo Ulugbek, Tashkent, Uzbekistan
  • Khodjiev S.S. National University Of Uzbekistan, Tashkent, Uzbekistan
  • Akhtamov M.A. National University Of Uzbekistan, Tashkent, Uzbekistan
  • Kozokov I.B. National University Of Uzbekistan, Tashkent, Uzbekistan
  • Abdurakhmonov Zh.A Institute Of Bioorganic Chemistry Named After Academician A.S.Sadikov, Tashkent, Uzbekistan
  • Mukhtorov A.A. Namangan State University, Uzbekistan
  • Mamadaminov R.R. Namangan State University, Uzbekistan

Keywords:

Intracellular Ca2 , cytosolic Ca2 , platelets

Abstract

In this work, the modified polysaccharide GSS-23 was studied for the functional activity of platelets. It has been determined that inhibition of the level of fluorescence of membrane-bound Ca2+ under the influence of GSS-23 is possibly associated with inhibition of calcium release from the depot. It has been shown that the inhibitory effect of GSS-23 on ADP-induced aggregation is associated with inhibition of the increase in the cytoplasmic concentration of Ca2+ from the platelet depot.

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References

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Published

2023-03-20

How to Cite

Khoshimov N.N., Ortikov M.M, Dedaboev J.I., Nasirov K.E., Khodjiev S.S., Akhtamov M.A., Kozokov I.B., Abdurakhmonov Zh.A, Mukhtorov A.A., & Mamadaminov R.R. (2023). CHANGE IN THE HEMOSTASIS SYSTEM UNDER THE INFLUENCE OF AN HSS-23. International Scientific and Current Research Conferences, 1(01), 78–81. Retrieved from https://www.orientalpublication.com/index.php/iscrc/article/view/898

Issue

VITAL ISSUES OF MODERN SCIENTIFIC RESEARCH

Section

Articles

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Copyright (c) 2023 Khoshimov N.N., Ortikov M.M, Dedaboev J.I., Nasirov K.E., Khodjiev S.S., Akhtamov M.A., Kozokov I.B., Abdurakhmonov Zh.A, Mukhtorov A.A., Mamadaminov R.R.

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